9 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... presents with coagulation ... * Severe coagulation ... #Thrombocytopenia ... #AFLP #obstetrics
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... presents with coagulation ... defects. 1) HELLP ... * Severe coagulation ... #HELLP #AFLP #Obstetrics
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
Post-Partum Hemorrhage - Differential ... purpura (TTP) • HELLP ... intravascular coagulation ... (DIC) • Anti-coagulation ... Algorithm #Causes #Obstetrics
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... features: Hemolysis, Thrombocytopenia ... #hepatology #obstetrics ... hepatitis #comparison #differential ... diagnosis #icp #HELLP
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... antiphospholipid syndrome - Pregnancy ... : HELLP - Mechanical ... #Differential #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... infiltration) Differential ... Preeclampsia, HELLP ... #Fatty #Liver #Pregnancy ... #hepatology #obstetrics
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... Extravascular #Causes #differential
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
Hypertensive Disorders of Pregnancy ... organ injury: thrombocytopenia ... preeclampsia patients • HELLP ... hypertension #htn #obstetrics ... #cardiology #differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Intravenous Drug Use • Pregnancy ... Heparin-induced thrombocytopenia ... intravascular coagulation ... pathophysiology #hematology #differential