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Purpura fulminans is a particularly malignant form of S-DIC associated with hemorrhagic infarction of dermal arteries.
Purpura fulminans ... Purpura fulminans ... is most often caused ... patients with purpura fulminans ... Photo #Purpura #Fulminans
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... hepatitis - Fulminant ... peritonitis #Ascites #Causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Coagulation disorders CAUSES ... Quantity: • Primary Causes ... • Secondary Causes ... Infectious Purpura Fulminans
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash: - Purpura fulminans ... Diagnosis #Algorithm #Causes
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
conglobata or fulminans ... conglobata or fulminans ... Rule out other causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
considered in all cases ... coagulation and other causes ... of purpura fulminans
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
bullae • Purpura fulminans ... Treat primary cause ... Coagulation #diagnosis #causes
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Iron overdose can cause ... Severe cases can ... In severe cases, ... Hepatic necrosis • Fulminant
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... rash → purpura fulminans
Capnocytophaga
GNR with long fusiform shape.  Fastidious facultative anaerobe that grows slowly and needs enriched agar
C.
= most common cause ... evolve to purpura fulminans