15 results
Pulmonary Function Tests (PFTs) - Interpretation Algorithm
 • Normal
 • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia
 • Chest
Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Differential Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... Differential #Diagnosis #Algorithm
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Phosphatase and Bilirubin ... hepatocyte - Elevation ... cytochromes) • Unconjugated ... MRP2 transports conjugated ... bilirubin into
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... in bone Total bilirubin ... (Conjugated/DBili ... Indirect bilirubin ... (Unconjugated)
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
of about 30% of normal ... of hemolysis or liver ... an increase in conjugated ... predominantly a mixed conjugated ... • Increase in conjugated
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Failure - Elevated conjugated ... and unconjugated ... bilirubin - Defects ... and excretion of bilirubin ... ALT and AST - Elevations
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... - +/- elevation ... function may be abnormal ... injury: ~ 1 Unconjugated ... Enzyme Elevation
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- +/- elevation ... week • Direct bilirubin ... Enzyme Elevation ... : • Bilirubin: ... blood cells Unconjugated
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
to 10-20-fold elevation ... , Bilirubin: <5 ... to 10-20-fold elevation ... , Bilirubin: <5 ... but variable ++, Bilirubin