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diagnosis hepatology differential lfts interpretation laboratory bilirubin gastroenterology hepatitis hyperbilirubinemia transaminitis aih autoimmune causes chemistry congenital creactiveprotein crp dehydrogenase direct
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... Hepatocellular injury ... 2: Cholestatic injury ... #FunctionTest # ... LFTs #Elevation
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Approach to Conjugated ... Differential Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... Differential #Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... function may be abnormal ... Enzyme Elevation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... - If both are normal ... or amyloid: • Elevation ... Enzyme Elevation ... blood cells Unconjugated
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... (LFTs) - Normal ... Direct bilirubin (Conjugated ... hepatocellular injury ... Indirect bilirubin (Unconjugated
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... Failure - Elevated conjugated ... and unconjugated ... ALT and AST - Elevations ... fold with acute liver
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of about 30% of normal ... of hemolysis or liver ... injury ... an increase in conjugated ... • Increase in conjugated
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... magnitude of enzyme elevation ... #Algorithm #Hepatology
C-REACTIVE PROTEIN Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
synthesized by the liver ... than 0.3 mg/L: Normal ... 0.3 to 1.0 mg/L: Normal ... or minor elevation ... Recent injury or
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