21 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs) Elevation ... vs bone Bili - Direct ... Obstructive) vs Indirect ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... ALP: - Enzymes ... Other causes of elevation ... consult ALP elevation ... Phosphatase #ALP #Elevation
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... Definition: T.bili elevation ... Hyperbilirubinemia #direct ... #Diagnosis #Algorithm
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Injury • AST/ALT elevation ... AnnKumfer #Liver #Enzymes ... Transaminitis #diagnosis #differential
Lead AVR on ECG
1. Acute myocardial infarction: ST elevation > 1.5 mm in aVR, indicative of
infarction: ST elevation ... to • aVR ST elevation ... in aVR • PR elevation ... : Differential diagnosis ... sensitive and to detect
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
value for this enzyme ... low, tests to detect ... platelet number Direct ... Mild-to-moderate elevation ... WBC count and differential
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias - Differential ... Diagnosis Algorithm ... • ↑ LDH • ↑ Indirect ... Membrane defects, Enzyme ... #Diagnosis #Algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Bilirubin - +/- elevation ... life: 1 week • Direct ... or amyloid: • Elevation ... Source of Liver Enzyme ... Elevation: •
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Diagnosis Algorithm ... Bilirubin - +/- elevation ... Half-life: 1 week • Direct ... Source of Liver Enzyme ... Elevation: •
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
to 10-20-fold elevation ... Elevated Liver enzymes ... to 10-20-fold elevation ... hepatitis #comparison #differential