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diagnosis hepatology differential lfts laboratory tests chemistry function hepatitis interpretation testing transaminitis abnormal aflp alkaline alkphos astalt comparison conjugated disease
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... vs bone Bili - Direct ... #FunctionTest # ... LFTs #Elevation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
- +/- elevation ... life: 1 week • Direct ... bilirubin: ↑ ... Enzyme Elevation ... : • Bilirubin:
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... - +/- elevation ... Half-life: 1 week • Direct ... Enzyme Elevation ... differential #diagnosis #algorithm
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
Liver Function Tests ... aminotransferase (ALT ... transpeptidase (GGT) - Bilirubin ... - Conjugated (Direct ... Prothrombin #Liver
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... hepatocyte - Elevation ... initial insult Bilirubin ... ASTALT #AlkPhos #Bilirubin
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
aminotransferase (ALT ... in bone Total bilirubin ... (TBili) Direct ... bilirubin (Conjugated ... Indirect bilirubin
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Definition: T.bili elevation ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct ... #bilirubin #Differential ... #Diagnosis #Algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... #Diagnosis #Algorithm
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
to 10-20-fold elevation ... , Bilirubin: <5 ... to 10-20-fold elevation ... , Bilirubin: <5 ... of Pregnancy (AFLP
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
and unconjugated bilirubin ... and excretion of bilirubin ... synthesis - Elevated ALT ... and AST - Elevations ... disease, ALT and
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