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diagnosis hepatology liver injury hepatitis interpretation causes chemistry drug elevated elevation enzymes function gastroenterology hepatocellular idiosyncratic induced liverenzymes liverfunctiontests management
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs ... abnormality vs bone Bili ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation ... #Transaminitis
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Function Tests (PFTs ... Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... #Algorithm #diagnosis
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal ... Hepatocellular Pattern #LFTs ... #transaminits # ... hepatology #diagnosis #differential ... #algorithm
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... ) - Differential ... (>1000): • DILI ... #Differential # ... Diagnosis #hepatology #transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... for Transaminitis ... Burak @kwburak #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... ) DILI Types: ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Levels: > 50x normal ... muscle 2-5x normal ... Injury #hepatology #LFTs ... #transaminitis ... #differential #diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Unconjugated Bili ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Liver Injury - Differential ... Liver #Injury #Differential ... Diagnosis #hepatology #algorithm ... #Transaminitis ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Diagnosis Algorithm ... disease US — Normal ... • Others #LFTs ... #Diagnosis #Algorithm
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