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diagnosis hepatology liver lfts causes acidosis bilirubin chemistry cholestatic classification conjugated deficiency enzymes fe gastroenterology hematology hepatitis hepatocellular hyperbilirubinemia injury
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs) Elevation ... vs bone Bili - Direct ... ALP ≥ 2x ULN R Value ... SinaiBmoreIMRes #Liver #FunctionTest ... #Transaminitis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Injury • AST/ALT elevation ... • R value = (ALT ... #Cholestatic #Transaminitis ... #diagnosis #differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... life: 1 week • Direct ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... Definition: T.bili elevation ... Hyperbilirubinemia #direct ... #Diagnosis #Algorithm
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... platelet number Direct ... Mild-to-moderate elevation ... WBC count and differential
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Iron Deficiency - Differential ... Diagnosis Algorithm ... sickle-cell, prosthatic valve ... Lactation, Low iron diet ... Iron #Deficiency #Differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Bilirubin - +/- elevation ... Half-life: 1 week • Direct ... #diagnosis #algorithm
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate Elevation ... Lactic Acidosis - Differential ... by cells as a direct ... to bolus these values ... #Differential #
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