19 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
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Causes of Extravascular ... Defects • G6PD ... Cold AIHA • PCH ... Diagnosis #Algorithm #Causes
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... Scl70 (in some cases ... Scl-70 (in some cases ... , PBC/SjS OS ... Antinuclear #Antibody #Testing
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting
Urine Drug Screens - Common drugs that may cause false positive tests 

Amphetamines:
Bupropion, Labetalol, Methylphenidate, Phenylephrine,
drugs that may cause ... Phencyclidine (PCP ... FalsePositive #Testing
Torsades de Pointes (TdP): Pathogenesis and Clinical Findings

Polymorphic ventricular tachycardia initiated by PVC in the setting
tachycardia initiated by PVC ... in the setting ... pathophysiology #cardiology #causes
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Crises can be precipitated ... with severe pain, lasting ... with co-existent G6PD
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
present in 15% of cases ... Demyelinating disease caused ... • JC-virus PCR ... of serum CrAg testing ... comparable to CSF testing
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Abdominal Pain Causes ... , physical and testing ... Consider cardiac causes ... genitourinary causes ... dysfunction • PSC
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Putrid sputum/sour-tasting ... Clindamycin in case ... of PCN allergy ... #differential #causes
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary
Fluid resuscitation can be beneficial when required or
Fluid Tolerance Testing ... measurement of CO via a PAC ... continuous (via heating ... cardiac output causes ... Responsiveness #Tolerance #testing