2002 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Unconjugated bilirubin LDH ... workup #diagnosis #hematology
Isolated Hyperbilirubinemia - Differential Diagnosis Algorithm
Direct Hyperbilirubinemia: Dubin-Johnson Syndrome, Rotor Syndrome
Indirect Hyperbilirubinemia: 
 - Trauma, Hematoma,
Transfusion - LDH ... Type I or II - LDH ... Diagnosis #Algorithm #hepatology
Intracranial Hemorrhages (ICH)

Epidural Hematoma vs Subdural Hematoma vs Subarachnoid Hemorrhage vs Intraparenchymal Hemorrhage

#Diagnosis #Radiology #Comparison #ICH
Hemorrhage #Hematoma #EDH ... #SDH #SAH #Epidural
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Inappropriate ADH ... physiologic stimulus to ADH ... 100 mmol/kg - ADH ... #Hyponatremia #Nephrology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
, Haptoglobin, LDH ... Reticulocyte index • ↑ LDH ... Management #Algorithm #hematology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Inappropriate ADH ... physiologic stimulus to ADH ... 100 mmol/kg - ADH ... #Hyponatremia #Nephrology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
antagonists 6) ADH ... Sites #Action #nephrology
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Diagnosis Algorithm ADH ... ADH Dependent: ... Algorithm #causes #nephrology
Conversion - Epoetin alfa (Procrit®) to Darbepoetin alfa (Aranesp™)

#Epoetin #Darbepoetin #Erythropoietin #Conversion #Table #ESAs #Procrit #Aranesp
#Pharmacology #Hematology ... #Nephrology
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
resistance to ADH ... inappropriate ADH ... #differential #nephrology