17 results
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Hyperglycemic Crisis - Algorithm ... 7.3 • Anion gap ... 7.3 • Anion gap ... Hyperglycemic #Crisis #Algorithm ... endocrinology #Diabetes #DM2
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
cases occur in ... significant anion gap ... a serum anion gap ... increase in anion gap ... until the anion gap
Causes of Metabolic Acidosis - Gap and Non-Gap - Differential Diagnosis Algorithm
 • Elevated Anion Gap
Acidosis - Gap ... and Non-Gap - Differential ... Elevated Anion Gap ... • Normal Anion Gap ... #Causes
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
and Euglycemic DKA ... ≤ 15 • Anion gap ... therapy in severe cases ... until the anion gap ... SGLT2 #Euglycemic #DKA
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
accompanied by an anion gap ... ketoacidosis (DKA ... ) - caused by complete ... to marked anion gap ... Glucosuria causes
Causes of Metabolic Acidosis with Elevated Anion Gap - Differential Diagnosis Algorithm
Elevated Anion Gap > 12
Causes of Metabolic ... Elevated Anion Gap ... Elevated Anion Gap ... correct anion gap ... 2.5 to the anion gap
Causes of Non-Gap Metabolic Acidosis - Differential Diagnosis Algorithm
Normal Anion Gap (<14) (Loss of Bicarbonate) -
Causes of Non-Gap ... Normal Anion Gap ... correct anion gap ... 2.5 to the anion gap ... #Causes
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
normally inactivates GLP ... -1 and GIP. ... combination therapy with GLP-I ... not definitively cause ... Pharmacology #Summary #DM2
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
no respiratory cause ... Labs show anion-gap ... Presentation seems like DKA ... exposure Symptoms: Nausea ... Shock Labs: Anion-Gap
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... out of cells may cause ... Treating DKA: 1) ... Follow the anion gap