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diagnosis differential management clinical algorithm causes pathophysiology endocrinology treatment nephrology criticalcare pharmacology pocus workup radiology signs symptoms table comparison video
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... excess: - ... #FeedbackLoop #
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... excess. ... GH excess prior ... GH excess after ... GrowthHormone #GH
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
excess occurs before ... • GH stimulates ... islet cell tumor, excess ... level (↑Sens) - GH ... (Lanreotide) ± GH
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
Puberty Onset • GH ... Excess • Hyperthyroidism
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
Prolactin #PRL #FeedbackLoop
Benign Adrenal Mass - Differential Diagnosis Algorithm Hyperplasia - Often Bilateral • Congenital Adrenal Hyperplasia • ACTH
Hyperplasia Androgen Excess ... DHEAS Estrogen Excess ... Glucocorticoid Excess ... ) Aldosterone Excess
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
growth hormone (GH
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Hypernatremia - Excess ... consciousness • No access
Causes of Polyuria - Differential Diagnosis Excess Intake of Water: • Primary polydipsia (a.k.a. "psychogenic polydipsia") •
Differential Diagnosis Excess ... Large volume IVF Excess ... diuresis): • Excess ... diuretics • Excess
Malignant Adrenal Mass - Differential Diagnosis Algorithm Suggestive of Malignancy: Inhomogenous Density, Delay in CT Contrast Washout
Biopsy Androgen Excess ... Hyperplasia) Estrogen Excess ... Glucocorticoid Excess ... ) Aldosterone Excess
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