31 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... excess: - ... #FeedbackLoop #
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... • Other rare causes ... GrowthHormone #GH
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
excess occurs before ... • GH stimulates ... islet cell tumor, excess ... (Lanreotide) ± GH ... or refractory cases
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Differential Diagnosis Algorithm ... Puberty Onset • GH ... Excess • Hyperthyroidism ... Differential #Diagnosis #Algorithm ... endocrinology #causes
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... Differential Diagnosis Algorithm ... Hypernatremia - Excess ... Differential #Diagnosis #Algorithm ... #Causes
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Primary (Essential) (95%) - Onset between age
and Secondary Causes ... Differential Diagnosis Algorithm ... Glucocorticoid excess ... Differential #Diagnosis #Algorithm ... #causes
Sellar / Pituitary Mass - Differential Diagnosis Algorithm
Adenoma - Primary Anterior Pituitary
 - Secreting
Differential Diagnosis Algorithm ... Prolactin • GH ... Differential #Diagnosis #Algorithm ... endocrinology #causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Defining the cause ... also look for excess ... differential #diagnosis #algorithm
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis Algorithm ... Cholecalciferol - Excess ... Differential #Diagnosis #Algorithm ... #causes #endocrinology
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Differential Diagnosis Algorithm ... • Adrenergic excess ... Differential #Diagnosis #Algorithm ... #Causes #Classification