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classification thrombocytopenia management signs vasculitis agglutinin ana antinuclear autoantibodies bruising cold criteria disease disorders eularacr hodgkins hyperkalemia lymphoma mimickers myopathy
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies ... Diagnosis and Lupus ... #Systemic #Lupus ... #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Inflammatory and Autoimmune ... Diseases: • Systemic ... lupus erythematosus ... #Diagnosis #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... ANA #patterns #rheumatology ... #diagnosis #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... Thrombocytopenia, Autoimmune ... hemolysis • Renal ... #Systemic #Lupus ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... #SLE #systemic ... #erythematosus # ... signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and a high ... lupus erythematosus ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Diagnosis: • hemolytic ... younger pts) Differential ... : High fevers, chills ... #anemia #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
. pylori test (GI ... symptoms/endemic ... MCV anemia (vegan ... #Diagnosis #Causes ... #Workup #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... (systemic lupus ... erythematosus) ... peds #pediatrics #diagnosis ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
neuropathy - GI ... Diagnosis: Systemic ... lupus erythematosus ... Symptoms (Sx) in ... #diagnosis #rheumatology
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