29 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... Normal CK - Myositis ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... , Arthralgia / arthritis ... , Myositis Dr ... #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Lupus Erythematosus ... (SLE) #Systemic ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
of hip (rare), Arthritis ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... : - Arthritis ... anemia 4% - Myositis ... #signs #symptoms ... #differential #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... , holster sign, ... , and arthritis ... #diagnosis #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
M DAMN SHARP - Lupus ... Antibody (ANA) M Mucositis ... cytopenias) A Arthritis ... IMDAMNSHARP #sle #systemic ... #rheumatology #
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Systemic Sclerosis ... involve DIP • Myositis ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... Lupus - with Systemic ... Lupus Erythematosus ... should have other symptoms ... Joint #Disorders #msk
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Juvenile Idiopathic Arthritis ... Sjögren Syndrome, Myositis ... ANA #patterns #rheumatology ... #diagnosis #differential