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diagnosis erythematosus management sle classification differential activation eularacr hemeonc hemophagocytic hlh lymphohistiocytosis macrophage mas monoclonal oncology paraproteinemias signs slicc symptoms
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria ... for Systemic Lupus ... pericarditis • Hematologic ... domain: Leukopenia, Thrombocytopenia ... #diagnosis #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLE Diagnostic Criteria ... - Systemic Lupus ... CLINICAL CRITERIA ... (<1000/MM3) - THROMBOCYTOPENIA ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Demyelinating syndromes ... Leucopenia/lymphopenia, Thrombocytopenia ... #Lupus #SLE #systemic ... symptoms #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... Diagnosis #Management #Hematology ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... lymphoma Multi-System ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... inflammation Others: • Lupus ... • Cogan Syndrome ... lupus erythematosus ... differential #diagnosis #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
standing for: - Thrombocytopenia ... disorders, including systemic ... lupus erythematosus ... in LNs and the systemic ... diagnosis #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... Cytopenias (anemia, thrombocytopenia ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... Diagnosis #Management #Hematology
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