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diagnosis antinuclear dermatology vasculitis alopecia antibodies antibody arthritis diffuse hairloss joint msk nuclear pain testing workup aortitis approach classification clues
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... erythematosus (SLE ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... Patterns and Associated ... erythematosus (SLE ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Scl70 (in some cases ... Scl-70 (in some cases ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... #diagnosis #algorithm ... #rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... the face (many differential ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... (RA), Systemic lupus ... erythematosus (SLE ... swinndong #Aortitis #Differential ... #Diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
: • SLE, SSc, ... Scl70 (in some cases ... : • SjS, SLE, DM ... #differential # ... diagnosis #rheumatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Focal) Differential ... Diagnosis Algorithm ... planopilaris Pattern ... • Discoid lupus ... #causes
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin Rash - Differential ... Diagnosis Algorithm ... Christmas tree pattern ... soles • Discoid Lupus ... #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... often causes arthritis ... such as systemic lupus ... SLE) • Urinalysis ... #diagnosis #rheumatology
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