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diagnosis differential aki algorithm classification causes injury kidney kidneyinjury rpgn vasculitis crisis hematology management monoclonal oncology paraproteinemias pediatrics progressive rapidly
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
(GN) in children ... SLE, systemic lupus ... #Glomerulonephritis ... #Algorithm #Nephrology ... #Peds #Pediatrics
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive Glomerulonephritis ... Complement: Post-strep GN ... , Lupus Nephritis ... Kidney: Anti-GBM Glomerulonephritis ... diagnosis #algorithm #rheumatology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
INTRINSINC RENAL Glomerulonephritides ... (GN) • Primary ... Post-infectious GN ... , Lupus Acute Tubular ... Differential #Diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Rapidly Progressive Glomerulonephritis ... IgA nephropathy, lupus ... post-infectious GN ... staining #Glomerulonephritis ... Differential #Diagnosis #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Prerenal: • Due to true volume loss or decreased
Acute Kidney Injury ... dye) • AIN (acute ... nephritis) • GN ... (glomerulonephritis ... Differential #Diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Rapidly Progressive Glomerulonephritis ... IgA, post-strep, lupus ... legionella) • Immune (lupus ... #KidneyInjury #Nephrology
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... Post-infectious glomerulonephritis ... disease - Acute ... causes: sepsis, meds ... Classification #diagnosis #nephrology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Immunotactoid GN ... -C3 GN • Cast ... to cold IgG • Lupus ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... - Necrotizing glomerulonephritis ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Renal Crisis: 1) Acute ... . pauci-immune GN ... , add other BP meds ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
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