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diagnosis differential management algorithm vasculitis disease signs symptoms joint oncology sle treatment comparison dermatology erythematosus msk ana antibodies antinuclear cardiology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... , Cogan's Syndrome ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #joint #pain #skin ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Vasculitis (e.g., PAN ... , Marfan syndrome ... conditions #joint #pain ... differential #diagnosis #rheumatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... • Epstein-Barr Virus ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... #Hematology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Lemierre's syndrome ... Malignancy: - Hematologic ... . autoimmune): Lupus ... , Rheumatoid arthritis ... Vasculitis (Temporal arteritis
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Loin pain hematuria ... syndrome: • ... Flank pain + gross ... Diagnostic of GN ... Hematuria: • Urethritis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... diagnosis #algorithm #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... Demyelinating syndromes ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
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