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diagnosis causes management signs sle algorithm erythematosus hematology pericarditis vasculitis antinuclear classification comparison disease joint mnemonic monoarthritis monoarticular msk myocarditis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Juvenile Idiopathic Arthritis ... #Antinuclear #Antibodies ... #ANA #patterns ... #rheumatology #diagnosis ... #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... context of other symptoms ... #rheumatology #diagnosis ... #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... SLE-Related Auto-Antibodies ... Diagnosis and Lupus ... #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... of Lumbar Spine and ... Lupus - with Systemic ... Lupus Erythematosus ... should have other symptoms
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... • Arthritis domain ... low C4, Low C3 and ... Highly specific antibodies ... #diagnosis #rheumatology
Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Regurgitation - Differential ... Inflammatory: Lupus ... Aortic Aneurysms and ... Degenerative: Systemic ... Diagnosis #Causes #cardiology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Neutropenia - Differential ... • Epstein-Barr Virus ... Destruction • Systemic ... Lupus Erythematosus ... • Rheumatoid Arthritis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... (RA), Systemic ... lupus erythematosus ... swinndong #Aortitis #Differential ... #Diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... Purpura Anti-GBM antibodies ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Inflammatory and ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... • Epstein-Barr virus ... #Diagnosis #Hematology
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