20 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... differential #diagnosis #rheumatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
• Epstein-Barr Virus ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... Algorithm #Causes #Hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... Polyarteritis Nodosa (PAN ... RD), Rheumatoid Arthritis ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Diseases: • Systemic lupus ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... burgdorferi • Virus ... - Autoimmune Rheumatologic ... • Hepatitis B virus ... Diagnosis #MSK #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... with temporal arteritis ... Diffuse muscle pain ... uncommon 5-15% of lupus ... diagnosis #comparison #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... lesions Abdominal pain ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Juvenile Idiopathic Arthritis ... scleroderma), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
• Systemic Lupus ... • Rheumatoid Arthritis ... Algorithm #Causes #Hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Immunotactoid GN ... Cryoglobulinemic GN ... -C3 GN • Cast ... to cold IgG • Lupus ... Paraproteinemias #Hematology