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diagnosis differential management symptoms syndrome erythematosus sle classification disease hematology joint oncology activation antibodies antinuclear aortitis arteritis autoantibodies autoimmune behcet
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... lesions Abdominal pain ... Glomerulonephritis Myositis ... erythematosus #signs
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
(GCA), Takayasu's ... vasculitis (rare ... (RA), Systemic ... lupus erythematosus ... Differential #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... branches • GCA ... lupus erythematosus ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... CRP GCA (Giant ... develop in pts with GCA ... tract: Abdominal pain ... Differential #Diagnosis #Rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Hypersensitivity vasculitis ... Sarcoidosis • GPA ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Neurologic system ... Lyme disease, Vasculitis ... conditions #joint #pain ... differential #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Juvenile Idiopathic Arthritis ... Sjögren Syndrome, Myositis ... Juvenile Idiopathic Arthritis ... #patterns #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... anemia 4% - Myositis ... autoantibodies #signs ... #differential #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... inflammatory vasculitis ... sx + signs/sx of ... them, but urgent rheumatology ... #Signs #Symptoms
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
neuropathy) • Systemic ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... to cold IgG • Lupus ... Paraproteinemias #Hematology
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