31 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Nodules • RA • Gout ... Tophi - Gout ... conditions #joint #pain ... differential #diagnosis #rheumatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
• Epstein-Barr Virus ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... Algorithm #Causes #Hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... , Cogan's Syndrome ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Crystal induced (Gout ... - Autoimmune Rheumatologic ... fever • Lyme • Gout ... • Hepatitis B virus ... Diagnosis #MSK #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Fever/Chills/Joint pain ... Effusions: - Gout ... - Pseudo gout ... Seronegative Reactive Syndrome ... Effusions: - Hematologic
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... capillary leak syndrome ... • Schnitzler syndrome ... Monoclonal #Gammopathy #Clinical ... Differential #Diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Fever is the main ... clinical manifestation ... SJIA], systemic lupus ... Diagnosis #Management #Hematology ... #Rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of hip (rare), Arthritis ... Demyelinating syndromes ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology