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diagnosis differential erythematosus systemic joint signs symptoms syndrome ana antinuclear classification disease druginduced msk patterns treatment vasculitis workup activation aortitis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... Juvenile Idiopathic Arthritis ... erythematosus (SLE ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... assay (IFA) is the main ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... Malar rash • SLE ... IBD • RA • SLE ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... involvement 3% SLE-Related ... Auto-Antibodies ... Lupusreference #SLE ... #differential #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... • Arthritis domain ... Highly specific antibodies ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... : • Joint pain ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... of hip (rare), Arthritis ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
- Autoimmune Rheumatologic ... • Hepatitis B virus ... • SLE • Psoriatic ... Symmetrical: • RA • SLE ... Diagnosis #MSK #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... Constitutional symptoms, Arthritis ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
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