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diagnosis vasculitis differential cryoglobulinemia monoclonal renal sle treatment algorithm cerebritis classification cns comparison crisis druginduced erythematosus glomerulonephritis involvement mixed nephritis
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) IgM
Non-hepatitis C virus ... Cryoglobulinemia ... MONOCLONAL CRYOGLOBULINEMIA ... #Vasculitis #Management ... #Rheumatology #
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
in 35% of mixed cryoglobulinemia ... #Vasculitis #Management ... #Rheumatology # ... Cryoglobulinemic ... #Nephrology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... , Cryoglobulinemia ... diagnosis #algorithm #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
& Cryoglobulinemic ... -C3 GN • Cast ... WM: Vasculitis (Cryoglobulinemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Diagnosis of Lupus ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... BaillouChloe #Lupus ... #rheumatology # ... nephrology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Usual therapeutic management ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... ANCA +MPO) • Cryoglobulinemic ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Membranoproliferative GN ... Nephrogenic DI Hematologic ... Vasculitis: • 7%, Cryoglobulinemia ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
of arteries Management ... . pauci-immune GN ... Renal #Crisis #rheumatology ... #nephrology #diagnosis ... #management
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