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differential causes glomerulonephritis acute algorithm classification neurology comparison diseases glomerular hematology injury kidney kidneyinjury membranoproliferative microscopy monoclonal mpgn neuropathy oncology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... - Differential Diagnosis ... Emboli, Thrombosis, Vasculitis ... • GN: ANCA, Anti-GBM ... #nephrology #causes
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... IgA nephropathy, lupus ... post-infectious GN ... #Differential #Diagnosis ... #Nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential Diagnosis ... Post-infectious GN ... , Lupus Acute Tubular ... #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... ) AKA: Mesangiocapillary ... GN • Active Urine ... , CFHR5 neph) MPGN ... #nephrology #diagnosis
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
/nephritis • Lupus ... Post-infectious GN ... • Amyloid RPGN ... glomerular #diseases #nephrology ... comparison #table #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... #rheumatology #
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
• Inflammatory/AI ... Guillain-Barre, Vasculitis ... , Sjogren's, Lupus ... #differential #diagnosis ... #causes #neurology
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
encephalitis, West Nile virus ... Toxoplasmosis AUTOIMMUNE/VASCULITIS ... Disease - Systemic Lupus ... #Differential #Diagnosis ... #Causes #Neurology
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