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diagnosis differential management erythematosus sle hematology symptoms vasculitis antinuclear antibodies causes neurology oncology autoantibodies dermatology disease mnemonic patterns sjogrens summary
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic Diseases ... connective tissue disease ... SLE), Sjogren's Syndrome ... #patterns #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... central nervous system ... - systemic ... lupus erythematosus ... Vessels #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... & Mu) Skin Manifestations ... Neurologic Manifestations ... to cold IgG • Lupus ... Sneddon-Wilkinson disease
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... Associated with skin manifestations ... block • Sjogren syndrome ... Summary #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... SLE), Sjogren's Syndrome ... : Lupus (SLE), Systemic ... Arthritis, Sjögren Syndrome ... #patterns #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Demyelinating Syndrome ... Cerebrovascular Disease ... CNS #neurology #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... Inflammatory and ... : • Systemic lupus ... • Epstein-Barr virus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Diagnosis Manifestations ... Auto-Antibodies: - ANA ... autoantibodies #signs ... #differential #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... main clinical manifestation ... • Hemorrhagic manifestations ... lupus erythematosus ... #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 1 • Clinical Manifestations ... Evolution: Chronic disease ... #Systemic #Erythematosus ... Management #Summary #rheumatology
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