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diagnosis erythematosus systemic management nephrology differential vasculitis antinuclear autoantibodies clinicopathology comparison criteria cryoglobulinemia cryoglobulins diseases druginduced eularacr glomerulonephritis laboratory renal
Renal Involvement in Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal #diseases #SLE ... #Systemic #Lupus ... venn #nephrology #nephritis ... #classification ... #types #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Non-autoimmune rheumatologic ... Kikuchi disease • Type-I ... Erythematosus #Diagnosis #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... nephritis, Class ... low C4, Low C3 and ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... treatment #management #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... lupus nephritis ... , neonatal lupus ... erythematosus #diagnosis #rheumatology ... #table #ANA
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... Erythematosus (SLE ... nephritis, NPSLE ... #sle #comparison ... #table #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
IgA nephropathy, lupus ... nephritis, cryoglobulinemia ... post-infectious GN ... autoAb against type ... Glomerulonephritis #RPGN #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... (e.g. systemic lupus ... erythematosus (SLE ... #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... such as systemic lupus ... SLE) • Urinalysis ... differential #diagnosis #rheumatology ... #classification
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... IV RTA, TYPE I ... • Interstitial nephritis ... Membranoproliferative GN ... Sjogrens #Syndrome #Rheumatology
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