11 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy #thrombocytopenic ... HemolyticUremicSyndrome #HUS #thrombocytopenia ... #Comparison #Diagnosis ... #Table #Hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... fibrinogen) • Thrombocytopenia ... #comparison #table ... differential #diagnosis #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... with coagulation defects ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... with coagulation defects ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Restrictive lung defect ... Leucopenia/lymphopenia, Thrombocytopenia ... #Lupus #SLE #systemic ... symptoms #diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SLE : systemic lupus ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... usually IgG) (e.g. lupus ... Intrinsic RBC Defects ... thalassemias), Membrane defects ... differential #diagnosis #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... Epidemiology: -10% of all lupus ... #sle #comparison ... #table #rheumatology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
/nephritis • Lupus ... Post-infectious GN ... • Membranous GN ... nephrology #pathology #comparison ... #table #diagnosis
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... #Presentation #comparison ... #Table #Diagnosis