36 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Rheumatoid Nodules, Pulmonary ... Instability, Felty's Syndrome ... RA #diagnosis #rheumatology ... #signs #symptoms
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... thrombocythemia), Autoimmune ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... skin thickening Signs ... calcinosis • Pulmonary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... Hodgkin lymphoma - Autoimmune ... thyroid, Sjogren syndrome ... test - Cogan sign ... - Peek sign
Severe Asthma Exacerbation
Signs of a Severe Asthma Exacerbation:
 • Vitals: ↑HR ↑RR ↓SpO2
 • High work
Exacerbation Signs ... of baseline Treatments ... #Exacerbation #CriticalCare ... #pulmonary #ventilation ... mechanical #management #treatment
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
• Obstructive: Pulmonary ... Abdominal compartment syndrome ... Dehydration Shock Treatment ... Differential #Diagnosis #criticalcare ... #algorithm #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... effusions, weight gain ... Imaging: CXR- pulmonary ... Renal Failure Treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... diagnosis #management #hematology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Summary Autoimmune ... Renal Syndromes ... #Renal #Syndromes ... diagnosis #management #treatment