16 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... other autoimmune diseases ... like rheumatoid arthritis ... RA) or systemic lupus ... #Syndrome #Pathophysiology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
temporalis (giant-cell ... arteritis) - ... - systemic lupus ... - Sjögren ... Vessels #Diagnosis #Rheumatology
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
: Systemic Lupus ... Erythematous, Systemic Vasculitis ... Systemic Sclerosis, Sjogren's ... , Still's Disease ... Differential #Diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... : Giant Cell Arteritis ... ANCA associated vasculitis ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
optic neuritis - Giant ... , Vasculitis (e.g ... enlargement - Sjögren's ... Scalp tenderness - Giant ... differential #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and often causes arthritis ... inflammation Others: • Lupus ... such as systemic lupus ... purpura: strong sign ... differential #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ANCA-associated vasculitis ... dermatomyositis, Sjogren ... Non-autoimmune rheumatologic ... • Mesenteric vasculitis ... Erythematosus #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... panuveitis, retinal vasculitis ... spondyloarthritis • Ocular: Giant ... diagnosis #management #signs ... #symptoms #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... arthralgia, and arthritis ... (e.g. systemic lupus ... SLE), rheumatoid arthritis ... classification #rheumatology