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Giant Cell (Temporal) Arteritis

Dr. Ann Marie Kumfer @AnnKumfer

#GiantCell #Temporal #Arteritis #Diagnosis #Management #GCA #rheumatology
Giant Cell (Temporal ... @AnnKumfer #GiantCell ... Management #GCA #rheumatology
2021 ACR/VF Guidelines for Management of Giant Cell Arteritis (GCA)

#GiantCell #Arteritis #GCA #ACR2021 #Management #rheumatology #algorithm
Management of Giant ... Arteritis (GCA) #GiantCell ... ACR2021 #Management #rheumatology
Temporal (Giant cell) Arteritis 
Risk Factors:
 • Age (almost never occurs before age 50) 
Clinical:
 •
Temporal (Giant ... #Temporal #GiantCell ... Arteritis #Diagnosis #Rheumatology
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
CRAB #SLIMCRAB #Oncology ... #HemeOnc #Hematology ... Hypercalcemia #Anemia
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Iron deficiency anemia ... - Anemia of chronic ... of chronic kidney ... Underproduction #Algorithm #hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Reactive: • Anemia ... Non-infectious (malignancy, rheumatologic ... Myelofibrosis • Chronic ... causes #Platelets #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... of Chronic Disease ... of Chronic Disease ... Algorithm #Causes #Hematology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... - Normocytic Anemia ... - Giant cells ... neurological findings #GiantCell
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... iron deficiency anemia ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... differential #diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... of chronic inflammation ... of chronic kidney ... of chronic inflammation ... diagnosis #causes #hematology