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management complications differential syndrome lupus msk psychiatry sle treatment urology adhd allergy als amyotrophic anaphylaxis anorexianervosa arteritis attentiondeficithyperactivedisorder barre behavioraldisorder
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... delivery of blood to limbs ... inflammation tends to cause ... #signs #symptoms ... #diagnosis #ExtraArticular
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Neurological Manifestations ... Subacute onset of limb ... coalescing tubercles • Limb ... • Caused by immune ... #Tuberculosis #diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... Escorial criteria uses ... Lateral #Sclerosis #neurology
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
Extrapulmonary manifestations ... of COVID-19 • Neurologic ... Gastrointestinal: Diarrhea, Nausea ... Extrapulmonary #Diagnosis ... #Signs #Symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Viral replication causes ... swelling - GI Manifestations ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... hair follicles -> causes ... #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... involvement: Intractable nausea ... #Optica #NMO #Manifestations ... #diagnosis #neurology ... #symptoms #signs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... Temporal/Proximal limb
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... ACS, AKI, acute limb ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis
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