59 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... and less common diseases ... diagnosis and treatment ... • Systemic lupus ... #neurology #inflammatory
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... Treatment: • ... #Lupus #Erythematosus ... #rheumatology #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... Cerebrovascular Disease ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... life-threatening • Treatment ... Evolution: Chronic disease ... #Systemic #Erythematosus
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... pain (20%) Renal disease ... Thrombocytopenia #Lupus
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... autoimmune disease ... Lupus - with Systemic ... Lupus Erythematosus ... like “butterfly rash
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus ... Petechial or purpuric rash ... lupus erythematosus ... Treatment: • Corticosteroids ... #Diagnosis #Management
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... PAN Pyoderma gangrenosum ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Immune Complex: Systemic ... lupus erythematosus ... Rheumatoid arthritis, Systemic ... differential #diagnosis #nephrology
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Pharmacological Treatment ... of Hepatorenal Syndrome ... Systemic vasoconstriction ... #HepatoRenal #Syndrome ... #Nephrology #Management