9 results
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... of hair, eyes, skin ... Porphyria cutanea tarda ... #skin #dermatology ... #causes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... #Classification ... #pathophysiology ... #differential #algorithm
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... diagnosis #types #classification
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
, Seizure disorders ... Encephalopathy, Cognitive Dysfunction ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... inflammation, leading
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Glycosylation - AGE cause ... increasing cytogenetic dysfunction ... - Breakdown of skin ... , resulting in skin ... #DiabeticFoot #pathophysiology
Skin Hyperpigmentation - Differential Diagnosis Algorithm
Diffuse:
 • Tanning
 • Adverse cutaneous drug eruption
 • Addison's disease
Skin Hyperpigmentation ... Porphyria cutanea tarda ... Hyperpigmentation #disorders ... #skin #dermatology ... #causes
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... Lower roots -> Cauda ... Non-compressive Spinal Cord Causes ... Bowel and bladder dysfunction ... differential #algorithm
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
Pathogenesis of Select Causes ... neuromuscular disorders ... CNS neurons -> Dysfunction ... colonic mucosa, leading ... #constipation #pathophysiology
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
LCH is a rare disorder ... various tissues, leading ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... for endocrine dysfunctions