921 results
Etiology of Splenic Infarction:
 • Hypercoagulability: Factor V Leiden, Antiphospholipid syndrome, Malignancy
 • Embolic disease: Atrial
neoplasm, Lymphoma, Gaucher ... Torsion: Wandering spleen ... Splenic #Infarction #spleen
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Amyloidosis • Gaucher's ... #Splenomegaly #Spleen
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... @YannNgyn #Gauchers
Lysosomal Storage Disorders

Mucolipidoses
 • I-Cell Disease

Mucopolysaccharidoses
 • Hurler
 • Hunter

Sphingolipidoses
 • Tay Sachs
 • Fabry
 •
• Fabry • Gaucher
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
exposure - Farmers, ranchers
Ashkenazi Jewish Genetic Screening Algorithm
 • Bloom syndrome
 • Canavan disease
 • Familial dysautonomia
 • Fanconi
anemia group C • Gaucher
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
Danon Disease, Gaucher
AAST spleen / splenic injury scale 

- Morgan Pinkston Eutermoser
@DenvERdgmd

#Diagnosis #Traumatic #Spleen #Splenic #Injury #Rupture #Scale
AAST spleen / splenic ... Diagnosis #Traumatic #Spleen
Cardiomyopathies 

Manifestations of cardiomyopathy (CM) range from microscopic alterations in cardiac myocytes to fulminant Heart Failure
(Amyloidosis, Gaucher
Lung Findings on Physical Exam
Crackles:
 • Short, discontinuous, sounds mostly heard during inspiration
 • Caused by
airways/alveoli as seen ... narrowed airways as seen ... consolidation gives spoken ... consolidation makes spoken