36 results
hematology oncology disease algorithm anemia aplastic causes classification eosinophilia leukemia mds myelodysplastic neurology product reactions symptoms vasculitis activation agglutinin apml
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... transformation to acute ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... : • Recurrent infections ... progress to MDS or acute ... #management #treatment ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- APLS • Acute ... pneumoniae Vascular Fragility ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... glucocorticoid treatment ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... presents as an acute ... #management #treatment ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, bleeding, infections ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... WBC >100k, + lab signs ... organ damage • Treatment ... #TLS #diagnosis ... #management #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... younger pts) Differential ... sensitize red blood ... chills, flank pain ... hemolytic #anemia #hematology
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