20 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Diseases #Nephritic
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient have glomerular ... casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology ... #Diagnosis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
of Glomerular Bleeding ... • Signs of glomerular ... RBC castsDiagnostic ... disease Renal ... #nephrology #renal
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... glomerular disease ... renal disease ... #nephrology #casts
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Calculi Glomerular ... RBCs and/or RBC casts ... epithelial side of glomerular ... endothelial side of glomerular
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
kidney injury (AKI ... Renal causes of ... vascular supply; glomerular ... GBM, Glomerular ... #Diagnosis #AKI
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... Renal: - Glomerular ... - Interstitial nephritis ... Medullary sponge kidney ... #Diagnosis #Causes
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... • Evidence of glomerular ... proteinuria, RBC casts ... → Refer to Nephrology ... for renal biopsy
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
) - Loss of kidney ... with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... INTRINSIC: - Glomerular ... white blood cell casts ... tubular cell casts ... or pigmented casts