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differential causes acute aki algorithm hematuria pulmonary rheumatology urology blood druginduced failure hypertension indications kidneyinjury management medications membranoproliferative mpgn nephritic
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - TTP/HUS • Glomerular ... glomerulonephritis ... #Injury #Classification ... #diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
) - Loss of kidney ... with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Glomerulonephritis ... Small-vessel vasculitis ... Interstitial nephritis ... • Inflammatory disease ... /phimosis #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Skin, glomeruli ... : glomerular ischemia ... purpura: strong sign ... Kidneys -> glomerulonephritis ... #rheumatology #classification
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... • Glomerulonephritis ... / Vasculits: ANCA ... #Injury #AKI #Workup ... #nephrology #causes
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Drug Induced Kidney ... Injury • Pre-Renal ... Vitamin C • Glomerular ... Disease: Drug induced ... vasculitis, TMA
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... Differential Diagnosis ... erythematosus, Rheumatoid arthritis ... sclerosis • Anti-Glomerular ... #nephrology
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Renal: - Glomerular ... syndrome, Other glomerulonephritis ... - Interstitial nephritis ... Medullary sponge kidney ... necrosis, Sickle cell disease
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... Sjogren's, rheumatoid arthritis ... (Dense deposit disease ... #MPGN #nephrology ... #diagnosis #renal
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... • Causes of Glomerular ... of glomerular hematuria ... Suggestive of glomerular ... disease Renal
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