11 results
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
severe, ADAMTS13 deficiency ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
mevalonate kinase deficiency ... Disease #diagnosis #management ... #treatment #rheumatology
Cardiff COVID-19 Daily checklist - Matt Morgan
A daily checklist for critically ill #covid19 patients. Concentrates on
, big wins and efficiency ... Haematology - ... criticalcare #SARSCoV2 #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
anemia, GATA2 deficiency ... , CTLA4 deficiency ... Anemia #oncology #hematology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
thrombopoietin deficiency ... causes #treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cellular immune deficiency ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
recipients w/ IgA deficiency ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
recipients w/ IgA deficiency ... Transfusion #diagnosis #management ... #hematology #reactions
Hemophilia A Prophylaxis (Factor Eight Deficiency)

Who Needs Prophylaxis?

Primary Prophylaxis:
 • Severe deficiency (activity level <1%) even
(Factor Eight Deficiency ... Prophylaxis: • Severe deficiency ... #FactorEight #Deficiency ... #hematology #management
Algorithm for managing FVII deficiency.

*Mild bleeding history includes minor epistaxis, menorrhagia, gastrointestinal bleeding, joint and soft
managing FVII deficiency ... #FVII #deficiency ... Factor7 #Algorithm #management ... #Hematology