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diagnosis neurology treatment hematology rheumatology signs aflp ascorbicacid cell cerebritis cns coagulation complications dic differential disseminated encephalopathy erythematosus fatty hemeonc
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... 64%) • Renal dysfunction ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... hepatocytes → Liver dysfunction ... postpartum): • Initial symptoms ... = nonspecific (nausea ... #pathophysiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... musculoskeletal symptoms ... Psychiatric symptoms ... • Poor wound healing ... , or any other cause
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Encephalopathy, Cognitive Dysfunction ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... inflammation, leading ... cerebritis #diagnosis #management
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... COMMON CAUSES + ... • Symptoms: Fever ... INITIAL MANAGEMENT
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... monophasic Pathophysiology ... Bilateral signs and/or symptoms ... • Infectious causes ... Myelitis #diagnosis #management
Pheochromocytoma - Diagnosis and Management Summary 10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
malignant, pediatric cases ... life • M=F Symptoms ... and other organ dysfunction ... Less common symptoms ... adrenoceptors, potentially leading
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... Neurological symptoms ... the underlying cause ... Syndrome #diagnosis #management
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... middle ear dysfunction ... -> Conductive hearing ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms
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