11 results
The Death Spiral: Increased RV Afterload (Acute PE) 
#Pathophysiology #PE #PulmonaryEmbolism #Embolism #DeathSpiral #Shock #RVDysfunction #RebelEM
Afterload (Acute PE ... ) #Pathophysiology ... #PE #PulmonaryEmbolism ... #DeathSpiral #Shock ... #RVDysfunction
Bedside Classification of Shock

Hypovolemic shock 

- Vomiting, diarrhea, overdiuresis 

- Hemorrhage (GI, peritoneal, RP) 

Distributive shock
Classification of Shock ... Hypovolemic shock ... RV failure - PE ... Acute valve dysfunction ... Prosthetic valve dysfunction
#Pathophysiology #PulmonaryEmbolism #RVDysfunction #Perils #DeathSpiral #Shock #Progression #curbsiders
#Pathophysiology ... PulmonaryEmbolism #RVDysfunction ... #DeathSpiral #Shock
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... death -> end-organ dysfunction ... Distributive Shock ... O2 delivery • PE
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Pathogenesis Erectile Dysfunction ... desired sexual performance ... Psychogenic Erectile Dysfunction ... #Pathophysiology
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... death -> end-organ dysfunction ... Distributive Shock ... O2 delivery • PE
Right Heart Catheterization - Pulmonary Artery Pressures and Calculations
PULMONARY VASCULAR RESISTANCE = (meanPAP-PCWP) / CO
 •
correlates with RV dysfunction ... 0.8 indicates RV dysfunction ... 0.63 predicted RV dysfunction ... or hypovolemic shock ... forward flow. e.g., PE
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... Life-threatening organ dysfunction ... cellular/metabolic dysfunction ... • Pathophysiology ... Infection + Organ dysfunction
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... 64%) • Renal dysfunction ... 25%) • Hepatic dysfunction ... • Respiratory dysfunction ... (16%) • Shock
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Infection (sepsis), PE ... severe APLS, organ dysfuxtion