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diagnosis differential management causes nephrology clinical hematology workup cardiology treatment microscopy urine syndrome dermatology pulmonary acute anemia criticalcare neurology pathophysiology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... overt cytoplasmic granules ... , and Auer rods. ... these features in ... most cases, even
Examples of varying granular and granular/waxy mixed casts: A: coarse granular/broad-waxy (and surrounding white blood cells);
and granular/waxy ... mixed casts: ... A: coarse granular ... surrounding white blood ... #Casts #Urine #
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
a linear red "Auer ... of crystallized granules ... most prevalent in ... Path #BloodSmear #Blood ... Smear #Microscopy #Auer
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... tubular proteinuria, granular ... casts/RTE; blend ... #Algorithm #nephrology
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
nonspecific; seen in ... concentrated urine Granular ... Muddy-brown" heme-granular ... disease Red blood ... Glomerulonephritis White blood
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... her peripheral blood ... decreased secondary granules ... , Auer rods in neutrophils ... Path #BloodSmear #Blood
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 Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Acellular Casts ... but can be seen in ... tubular necrosis (ATN ... Non-specific; seen in ... ) • Granular Casts
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
from anywhere in ... = inflammation in ... renal disease • Granular ... • “Muddy brown cast ... crystals can be found in
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Differential Diagnosis Algorithm ... , Sudan Black, Auer ... @AmyChung #Blood ... Differential #Diagnosis #Algorithm
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... unilateral flank pain ... proteinuria, RBC casts ... Hematuria #Diagnosis #Algorithm ... Workup #urology #blood
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