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diagnosis differential hematology oncology clinical generalized lymphadenopathy rods smear acute apl auerrods blood bloodsmear dermatology diffuse endocrinology lad microscopy path
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... overt cytoplasmic granules ... , and Auer rods. ... features in most cases ... KyleBradleyMD #Auer
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
a linear red "Auer ... of crystallized granules ... acute myelogenous leukemia ... Smear #Microscopy #Auer
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... promyelocytic leukemia ... decreased secondary granules ... acute myeloid leukemia ... mixed lineage leukemia
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 Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Chronic leukemia ... -> AML: Blast crises ... Age: 50-60 • Auer ... distinctive primary granules
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Lymphoblastic Leukemia ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • Neoplastic (Leukemia ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Differential Diagnosis Algorithm ... Chronic myelogenous leukemia ... Polycythemia vera Acute Leukemia ... #Causes #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
histamine in their granules ... Chronic myeloid leukemia ... Acute myeloid leukemia ... Chickenpox Other Causes ... Differential #Diagnosis #causes
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... tubular proteinuria, granular ... casts/RTE; blend ... Nephritis #AIN #Algorithm
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Differential Diagnosis Algorithm ... • Lymphoma • Leukemia ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
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