1460 results
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
over-secretion of growth ... #Acromegaly #Signs
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... Hormone (GH) Growth ... pathway -> Incr cell growth ... activates lipolysis Signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... excess prior to growth ... GH excess after growth ... Overproduction #diagnosis #signs
Symptoms of Hypophosphatemia
 • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue
 • Hematologic:
Osteomalacia, Growth ... Phosphate #Symptoms #Signs
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... Male-pattern hair growth ... Accelerated childhood growth ... Hydroxylase #Deficiency #Signs
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... , Malnutrition Signs ... density, Impaired growth ... Deficiency #diagnosis #signs
Transverse lines of the fingernails. (A) Beau’s lines (arrows) of the thumbnail. (B) Mees’ lines (arrowheads)
be caused by a growth ... are a typical sign ... distally as the nail grows ... of nail matrix growth
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Osteoblasts and Growth ... pathophysiology #signs
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Hypopituitarism • Growth ... Pituitary #Tumors #Signs
Hockey Puck Sign of Moraxella Catarrhalis on Culture

Adjacent to a large growth of Pseudomonas aeruginosa

Rich Davis,
Hockey Puck Sign ... Adjacent to a large growth ... #HockeyPuck #Sign