11 results
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
for SGLT2i in HF ... in HFrEF on GDMT ... outcomes in HFrEF ... SGLT2 #inhibitors #EBM ... visualabstract #table
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
ejection fraction, treatment ... Spironolactone #HFpEF ... #dCHF #Cardiology ... #EBM #VisualAbstract
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... normal - Infection (EBV ... 1 - Ischemia, CHF ... Patterns #Liver #Injury ... #hepatology #LFTs
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... C, A, E, B, D, EBV ... Budd-Chiari, Congestion/CHF ... Sophia_Hayes_MD #Liver #Injury ... Acute #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... of Acute Liver Injury ... syndrome, Congestion/CHF ... HBV, HCV, HEV, EBV ... diagnosis #algorithm #hepatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... : Age>60, CKD, CHF ... : No • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... involvement, Kidney injury ... non-essential drug/HDS treatments ... HBV, HCV, HEV, EBV ... Diagnosis #Algorithm #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... to BM) • Constitutional ... Parvovirus B19 - EBV ... aplastic anemia Treatment ... Anemia #oncology #hematology
Monteggia Fracture 
Fracture of proximal ulnar shaft with radial head dislocation. Remember “MUGR” to recall where
syndrome, ligamentous injury ... • If stable ... repair MH/CCF ... /CWRU EM Res @MetroHealth_EM
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, rhabdo/crush injury ... Na delivery): CHF ... Elimination (see Table ... Stabilization Treatments ... Redistribution Treatments