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management differential chronic cll workup anemia aplastic cancer classification coagulation cvid dic diffuse disorders disseminated hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Algorithm Reactive ... • CMV • HIV ... #Algorithm #Causes ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... chemotherapy for low-risk disease ... • Indications ... #Leukemia #oncology ... #hematology #hemeonc
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... Autoimmune • ITP • SLE ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... #Algorithm #Causes ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... Orange or Hep C Clinical ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential Diagnosis ... family history - Medications ... test, ANA (e.g., SLE ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... infiltrates (anemia, thrombocytopenia ... Leukemia): • Lymphocytes ... #Hematology #Oncology ... #Diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Severe Liver Disease ... #causes #treatment ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... - Antithyroid medications ... virus (EBV) • Leukemia ... #hematology #diagnosis
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