25 results
Interpretation of Hepatitis B Serologies 
HBsAg - HBcAb (total) - HBcAb (IgM) - HBsAb
Susceptible to HBV
Immune
Acute HBV Chronic ... HBV Resolved infection ... #Serologies #serology ... #diagnosis #hepatology ... interpreation #testing
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
Serology and Interpretation ... B - Chronic hepatitis ... less commonly, infection ... #HBV #Serology ... diagnosis #laboratory #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... HBV infections ... who have serologic ... Chronic Hepatitis ... Management #Treatment #Hepatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... Positive Coombs testing ... , EBV, HIV, rubella ... younger pts) Differential ... #hematology #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... Myelofibrosis Infectious ... Iron deficiency anemia ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Diagnosis Algorithm ... • CMV • HIV ... Tuberculosis • Hepatitis ... Age > 50 • Chronic ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Infection) High ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Malignancy Infectious ... Epstein-Barr Virus • Hepatitis ... • HIV Autoimmune
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold agglutinins ... inclusions - If infection ... #workup #hematology ... #testing
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... hemolysis, deficiency anemia ... : Chronic infections ... #hematology