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management disorders chronic mds myelodysplastic syndromes thrombocytopenia acidosis arteritis cancer cll cord elevation eosinophil eosinophilia fatigue gap gca giantcell globulin
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... #Diagnosis #Algorithm ... #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Anemia Clinical ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... for workup, including ... #Diagnosis #Algorithm ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #hematology #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... (CVID, WAS), (neurologic ... #Diagnosis #Causes ... #Workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... glucocorticoid treatment ... may be indicated ... #Differential # ... diagnosis #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... • Anemia • ... Malignancy Infectious ... Hepatitis • HIV ... #Diagnosis #Algorithm
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Megaloblastic anemia-rare ... white blood cell aplasia ... #diagnosis #causes ... #hematology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
BEE Syndromes - ... and treatment can ... pachymeningitis • HIV ... MRI lesions and clinical ... #Syndromes #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Anemia • Aplastic ... blood count with differential ... #diagnosis #hematology ... #oncology
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