22 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... uremic syndrome (HUS ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... differential #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis ... and RES-mediated hemolysis ... circulation - Infections ... MAHA (TTP, DIC, HUS ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic ... SLE) - Viral infections ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Medial Approach Knee Intra-articular Corticosteroid Injection 

Landmark 1/3 to 1/2 way from top of patella. Find
Corticosteroid Injection ... #clinical #video ... #physicalexam #procedure ... #msk #orthopedics ... #sports #rheumatology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... drug induced • Infections ... • MAHA: TTP, HUS ... udaygulati #Hemolytic ... classification #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... DIC, TTP, HELLP, HUS ... inclusions - If infection ... ARUPConsult @ARUPLabs #Hemolytic ... Algorithm #workup #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... Internal (RBC) - Infections ... Urobilinogen #Hemolysis ... Differential #Diagnosis #hematology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vulnificus skin infection ... rapidly evolving rash ... hemochromatosis, hemolytic ... anemia, CKD, hiv ... #dermatology #legs
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Due to Viral infection ... Diagnosis: • hemolytic ... • Compensated hemolysis ... Mycoplasma, EBV, HIV ... #anemia #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
menstrual - Recent procedures ... - Infection exposure ... , HCV - Alcohol ... or if a primary hematologic ... Causes #Workup #hematology